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The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene.
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There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
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U-138 MG is a polygonal cell that was isolated from the brain of a 47-year-old, White, male with glioblastoma, grade IV This is one of a number of cell lines derived from malignant gliomas (see also ATCC HTB-14 and ATCC HTB-15 ) by J. Ponten and associates from 1966 to 1969. The cell line U-138 MG can be used in neuroscience research.
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VERO 76 is a cell line exhibiting epithelial morphology that was isolated in 1968 from the kidney of a patient. This cell line was deposited EM Earleyand.
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NCI-H2023 [H2023] is a cell line that was isolated from the lungs of a 26-year-old, White, male patient with stage 3A non-small cell lung cancer: adenocarcinoma. This product has applications in cancer research.
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